This book discusses the goals and methods of modern pesticide toxicology and describes quantitative criteria needed to assess their toxicity and hazard to man. it emphasizes the cumulative effect of long-term exposure to pesticides and the adaptive response of the organism. Furthermore, it considers the biochemical mechanisms responsible for the action of pesticides, and the effects of combined, concomitant and joint pesticide exposure (the latter two terms are adopted in Soviet scientific literature) with other chemicals or with physical environmental factors. Some of the topics covered hear on clinical aspects and diagnosis of pesticide poisonings and current therapeutic techniques.