This new report builds on the previous Sick Water? report (https://wedocs.unep.org/20.500.11822/9156), starting with the premise that wastewater is an important and valuable resource that can also help avoid costs of pollution and biodiversity loss. It aims to inspire policy and decision makers to be proactive in leading transformational change in sustainable wastewater management by closing the loop in the water cycle and realizing the opportunities to reuse the resources that can be recovered from wastewater.