Cities in Latin America and the Caribbean not only face inadequate land planning, housing deficits, and inefficient and unevenly distributed infrastructure; they also lack landscape or watershed planning that integrates ecosystem services into their sustainable development. These high levels of exposure to climate risks compel us to recognize the need to change the current unsustainable model of regional urbanization. Nature-Based Solutions (NbS) are an effective way to strengthen the resilience of urban communities by enhancing the natural functions of ecosystems and providing social, ecological, and economic benefits. This publication aims at providing tools for those involved in urban planning to more effectively integrate climate risks and the opportunities offered by the ecosystem context of each city. This way, it seeks to contribute to Latin America and the Caribbean resilient urban development.