In Kigali Fact Sheet 6 the development of a national HFC phase-down strategy is discussed. That Fact Sheet gives background information on the “core actions” that can be used to deliver the required cuts in HFC consumption. It was stressed that the most important long-term core action is to use lower GWP alternatives to HFCs in all new equipment. In this Fact Sheet we show how the choice of refrigerant selected in new equipment has a strong influence on the rate of HFC phase-down.