Part II provides insights into progress made towards the 2020 goal to “achieve, by 2020, that chemicals are used and produced in ways that lead to the minimization of significant adverse effects on human health and the environment [...]”. It also addresses emerging policy issues identified by the International Conference on Chemicals Management (ICCM) and issues where emerging evidence indicates a risk to human health and the environment. Part II includes the following chapters: 1/ International agreements and frameworks on chemicals and waste; 2/ Reporting schemes and indicators under international agreements and frameworks; 3/ Achieving the 2020 goal: what do we know?; 4/ Emerging policy issues and other issues of concern; 5/ Other issues where emerging evidence indicates a risk; 6/ Overall progress towards the 2020 goal: what have we learned?; and Annex: Other issues where emerging evidence indicates a risk.