This publication provides practical guidance for policymakers and service providers to create a policy context that is conducive to eco-innovation, thus enabling systemic changes in production and consumption patterns. More specifically, this publication aims to help policymakers better understand the benefits of eco-innovation and the contribution it can make towards sustainable development. It provides guidance on how SCP policy and Science, Technology and Industry (STI) policy can support eco-innovation and how a conducive policy context for eco-innovation can be set. Finally, it aims to inform service providers on how they can effectively engage at the different stages of the SCP policy cycle, scaling up their interventions in order to improve the context for eco-innovation. Given the fact that service providers work mainly with SMEs, the focus is particularly on policies that can support those enterprises to follow an eco-innovative path. This publication presents a broad range of examples across industry sectors, environmental aspects and geographical areas. It illustrates the results of national level policy activities implemented in Colombia, Peru, Kenya and Vietnam.