In North America, air pollution remains a serious health risk despite the large improvements in air quality that have been achieved by regulatory measures implemented under the Canadian Environmental Protection Act (CEPA) and the U.S. Clean Air Act (CAA). In addition, disparities in air pollution exposure by socioeconomic status persist and the burden of disease attributable to air pollution in North America is significant. This report provides a review of policy actions of Canada and the United States of America per the mandate provided by United Nations Environment Assembly (UNEA) resolution 3/8 on Preventing and reducing air pollution to improve air quality globally. This report builds on the United Nations Environment Programme (UNEP) report Actions on Air Quality 2021, which was recently released to provide an update on actions undertaken by countries around the world, focusing on a set of measures that, if adopted, would significantly improve air quality. This North American regional report documents more in-depth actions in key sectors as well as regional trends and priorities.