A two-page summary of the information on endocrine-disrupting chemicals (EDCs) contained in the 2020 UNEP Assessment Report on Issues of Concern: Chemicals and Waste Issues Posing Risks to Human Health and the Environment and the 2019 Global Chemicals Outlook II. An EDC is an exogenous substance or mixture that alters function(s) of the endocrine system and consequently causes adverse health effects in an intact organism, or its progeny, or (sub)populations.