The study aims to restore understanding about the connection between policies for addressing chemical pollution, the accumulation of waste and biodiversity loss and the need to continue pursuing an integrated approach across the obligations and activities of the chemicals and waste and biodiversity clusters of multilateral environmental agreements (MEAs). A half a century ago, a holistic approach for such policies was presented by Rachel Carson in her book Silent Spring that revealed the detrimental impacts of DDT to wildlife, birds, bees, agricultural animals, domestic pets, and even humans, which gave birth to the mod-ern environmental movement.1 However, over time, this integrated view was lost as the international community adopted a plethora of MEAs with each of them having a specific objective, scope, and set of obligations that are governed by their own decision-making bodies. This instilled a separation in the global environmental governance system for the development and follow-up of policies and activities for ad-dressing biodiversity and chemicals and waste issues that will need to be brought together to address these challenges more effectively, and, ultimately, to help overcome the triple planetary crises.