The Summary for Policy Makers of the second edition of the MED QSR was mandated by the 23rd Ordinary Meeting of the Contracting Parties to the Convention for the Protection of the Marine Environment and the Coastal Region of the Mediterranean and its Protocols (COP 23), with the scope to serve as one of the communication products of the 2023 MED QSR, and was prepared in close collaboration with the Contracting Parties to the Barcelona Convention. The Summary for Policy Makers provides at a glance the key highlights, assessment findings, and recommendations towards achieving Good Environmental Status (GES) for the Mediterranean Sea and Coast in line with the respective Ecological Objectives (EOs) and Common Indicators (CIs) of the Integrated Monitoring and Assessment Programme (IMAP).