Penicillia frequently occur in feeds and foods. Many isolates of this genus are Toxinogenic and thus 1. impair the health of domestic animals, 2. cause residues in organs and meat due to carry over, 3. Synthesis mycotoxins in moldy meat products, and 4. may be hazardous for mold-fermented foods. The results of our laboratory gathered in these respects are summarized in this contribution.