This document provides revised guidelines on the project application process to the sixth round of applications for funding from the Special Programme Trust Fund. The Special Programme is one of two key complementary elements of dedicated external financing under the integrated approach, with the Global Environment Facility (GEF) being the second element. These guidelines aim to assist applicants in understanding the scope of the Special Programme and the proposed projects to support institutional strengthening at the national level for implementation of the Basel, Rotterdam, and Stockholm Conventions, the Minamata Convention and the Strategic Approach to International Chemicals Management. The application guidelines are structured as follows: Chapter 2 describes the Special Programme and provides logistical facts about the submission of a project proposal. This chapter also describes the next steps once the project application is submitted to the Special Programme Secretariat. Chapter 3 provides information on possible areas of on which projects can focus within the context of the terms of reference of the Special Programme and taking into account national priorities and information obtained following preparatory national consultations prior to developing the project proposal. Chapter 4 provides an overview on gender consideration and UNEP safeguard standards that should be considered when drafting and implementing Special Programme projects. Chapter 5 provides a summary of considerations relating to monitoring and evaluation. Chapter 6 provides links to additional resources that can be used by applicants. Annex I sets out the terms of reference of the Special Programme. Annex II sets out the Governing council decision on the integrated approach; Annex III provides an overview of the possible scope of projects and Annex IV summarizes the appraisal criteria.