This paper outlines UNEP’s role in the Science-Policy Interface, reflects on past successes and considers the challenges ahead. It also explores how UNEP’s work can be strengthened in the science-policy field in the medium to longer term. The paper focuses on proposals for new models for a more effective Science-Policy Interface; the role of technology; behavioural change; equity; and participation in enhanced management of the environment. The new models propose ways to strengthen the Science-Policy Interface to support global environmental governance. These new models would ensure processes that are both socially relevant and economically robust, and contribute to intergenerational equity. The paper then introduces a select number of issues that need consideration by UNEP and its stakeholders to secure the future of the planet.