Integrated approaches to sustainable infrastructure have been well conceptualized, but good examples at the systems-level are less commonly found around the world. With “mega trends” emerging in investment, natural resource and energy use, a normative framework is required to guide and illustrate priority directions. This collection of case studies illustrates some of the salient aspects of the International Good Practice Principles for Sustainable Infrastructure. Documenting integrated approaches in action, it provides real-world examples of the good practices set out in the principles.